清脆的
重组酶
计算机科学
计算生物学
DNA
基因组编辑
生物
遗传学
基因
重组
作者
Debmitra Sen,Poulami Mukhopadhyay
出处
期刊:BioSystems
[Elsevier]
日期:2023-03-01
卷期号:225: 104870-104870
标识
DOI:10.1016/j.biosystems.2023.104870
摘要
The necessity to record and store biological data is increasing in due course of time. However, it is quite difficult to understand biological mechanisms and keep a track of these events in some storage mediums. DNA (deoxyribonucleic acid) is the best candidate for the storage of cellular events in the biological system. It is energy efficient as well as stable at the same time. DNA-based writers and memory devices are continually evolving and finding new avenues in terms of their wide range of applications. Among all the DNA-based storage devices that employ enzymes like recombinases, nucleases, integrases, and polymerases, one of the most popular tools used for these devices is the emerging and versatile CRISPR Cas technology. CRISPR Cas is a prokaryotic immune system that keeps a memory of viral attacks and protects prokaryotes from potential future infections. The main aim of this short review is to study such molecular recorders and writers that employ CRISPR Cas technologies and obtain an in-depth overview of the mechanisms involved and the applications of these molecular devices.
科研通智能强力驱动
Strongly Powered by AbleSci AI