C型凝集素
凝集素
受体
细胞生物学
信号转导衔接蛋白
生物
信号转导
模式识别受体
刺激
树突状细胞
免疫学
免疫系统
先天免疫系统
神经科学
生物化学
作者
Robert Blamberg,Roland Lang
出处
期刊:Science Signaling
[American Association for the Advancement of Science (AAAS)]
日期:2023-03-07
卷期号:16 (775)
标识
DOI:10.1126/scisignal.adg4314
摘要
The transcriptional response of macrophages and dendritic cells to stimulation of pattern recognition receptors can be unexpectedly distinct. In this issue of Science Signaling , Watanabe et al. demonstrate that IL-2 is differentially induced by the closely related C-type lectin receptors Dectin-2 and Mincle and reveal early signaling through the adaptor protein FcRγ as a critical mechanism.
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