纳米医学
观点
医学
从长凳到床边
癌症
临床试验
重症监护医学
医学物理学
纳米技术
病理
内科学
艺术
材料科学
纳米颗粒
视觉艺术
作者
Pengfei Zhang,Yufen Xiao,Xin Sun,Xin Lin,Seyoung Koo,Alexey V. Yaremenko,Duotian Qin,Na Kong,Omid C. Farokhzad,Wei Tao
出处
期刊:Med
[Elsevier]
日期:2023-03-01
卷期号:4 (3): 147-167
被引量:39
标识
DOI:10.1016/j.medj.2022.12.001
摘要
With the integration of nanotechnology into the medical field at large, great strides have been made in the development of nanomedicines for tackling different diseases, including cancers. To date, various cancer nanomedicines have demonstrated success in preclinical studies, improving therapeutic outcomes, prolonging survival, and/or decreasing side effects. However, the translation from bench to bedside remains challenging. While a number of nanomedicines have entered clinical trials, only a few have been approved for clinical applications. In this review, we highlight the most recent progress in cancer nanomedicine, discuss current clinical advances and challenges for the translation of cancer nanomedicines, and provide our viewpoints on accelerating clinical translation. We expect this review to benefit the future development of cancer nanotherapeutics specifically from the clinical perspective.
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