多神经根神经病
医学
髓鞘
糖蛋白
免疫学
髓鞘相关糖蛋白
皮肤病科
格林-巴利综合征
内科学
生物
分子生物学
中枢神经系统
作者
Masanori Nakajima,Kenichi Kaida
出处
期刊:PubMed
日期:2025-01-01
卷期号:77 (1): 35-42
标识
DOI:10.11477/mf.188160960770010035
摘要
Anti-myelin-associated glycoprotein (Anti-MAG) neuropathy and autoimmune nodopathies with antibodies targeting nodal or paranodal proteins have recently been reclassified as distinct conditions, separate from chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). This distinction is based on the clinical homogeneity observed in antibody-positive cases, their unique response to treatment compared to CIDP, and evidence indicating the pathogenic role of these autoantibodies. The significance of identifying conditions outside the CIDP category lies in the elucidation of their distinct pathological mechanisms and providing appropriate immunotherapy accordingly. We hope that the various pathologies currently grouped under CIDP will be further clarified in the future, leading to the elimination of CIDP variants with different pathophysiologies.
科研通智能强力驱动
Strongly Powered by AbleSci AI