异质性
线粒体DNA
体细胞
生物
癌变
癌症的体细胞进化
单细胞分析
突变
细胞
遗传学
分子生物学
癌症研究
癌症
基因
作者
Kaixiang Zhou,Zhenni Wang,Wenjie Guo,Fanfan Xie,Qing Yuan,Shanshan Guo,Huanqin Zhang,Yang Liu,Xiwen Gu,Wenjie Song,Xu Guo,Jinliang Xing
出处
期刊:Hepatology
[Lippincott Williams & Wilkins]
日期:2024-10-11
卷期号:82 (1): 59-76
被引量:6
标识
DOI:10.1097/hep.0000000000001113
摘要
Our study unravels the landscape of single-cell somatic mtDNA mutations in HCC tissues and reveals the bidirectional evolution of unstable mtDNA mutations, with potential implications for HCC stratification and therapeutic intervention.
科研通智能强力驱动
Strongly Powered by AbleSci AI