脂肪酸结合蛋白
计算生物学
运输机
生物标志物
生物
生物信息学
神经科学
生物化学
基因
作者
Binyue Xu,Lu Chen,Yu Zhan,Karl Nelson S. Marquez,Lvjia Zhuo,Shasha Qi,Jinyu Zhu,Ying He,Xudong Chen,Hao Zhang,Yingying Shen,Gongxing Chen,Jianzhong Gu,Yong Guo,Shuiping Liu,Tian Xie
标识
DOI:10.3389/fcell.2022.857919
摘要
In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter, has been widely researched with the help of modern genetic technology. Emerging evidence suggests its critical role in regulating lipid transport, homeostasis, and metabolism. Its involvement in the pathogenesis of various diseases such as metabolic syndrome, skin diseases, cancer, and neurological diseases is the key to understanding the true nature of the protein. This makes FABP5 be a promising component for numerous clinical applications. This review has summarized the most recent advances in the research of FABP5 in modulating cellular processes, providing an in-depth analysis of the protein’s biological properties, biological functions, and mechanisms involved in various diseases. In addition, we have discussed the possibility of using FABP5 as a new diagnostic biomarker and therapeutic target for human diseases, shedding light on challenges facing future research.
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