丹吉尔病
血脂异常
血脂谱
内科学
糖尿病
败血症
脂质代谢
胆固醇
内分泌学
医学
脂蛋白
代谢紊乱
生物
生物化学
ABCA1
运输机
基因
作者
Carlos Palacio,Irene Alexandraki,Roger L. Bertholf,Arshag D. Mooradian
出处
期刊:PubMed
日期:2011-01-01
卷期号:41 (2): 150-3
被引量:4
摘要
Tangier disease is a rare genetic disorder of lipid metabolism characterized by low concentrations of plasma high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol with normal or elevated levels of triglycerides. In this case report we describe a patient with diabetes who experienced an episode of urosepsis with a plasma lipid profile resembling Tangier disease. Experimental evidence in the literature suggests that similar lipid changes may occur due to cytokines released during sepsis. Clinicians should be aware of these changes to avoid misdiagnosis of lipid disorders.
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