化学
多胺
结合
固相合成
组合化学
化学合成
生物化学
体外
肽
数学分析
数学
作者
Vladimir Kuksa,Robert Buchan,Paul Kong Thoo Lin
出处
期刊:Synthesis
[Thieme Medical Publishers (Germany)]
日期:2000-01-01
卷期号:2000 (09): 1189-1207
被引量:93
摘要
The role of polyamines in biological systems is now well recognised. In this review an introduction to polyamines and their biological significance is first outlined. The main focus of this review is on the chemical strategies used in the synthesis of polyamines, their derivatives, analogues and conjugates. Recent developments in solid phase synthesis of more complex polyamine molecules is also covered.
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