慢性阻塞性肺病
表观遗传学
氧化应激
医学
肺病
疾病
炎症
生物信息学
免疫学
病理
生物
内科学
遗传学
基因
作者
Taru Aggarwal,Ridhima Wadhwa,Noopur Thapliyal,Kanishka Sharma,Varsha Rani,Pawan Kumar Maurya
摘要
Abstract A large body of evidence indicates that chronic obstructive pulmonary disorder (COPD) is accompanied by oxidative stress and inflammatory and genetic pathways. Epidemiological studies indicate that COPD is a major cause of mortality and morbidity in the world. Recent research development in COPD focuses on accelerated aging and various oxidative stress biomarkers. It involves the clinical manifestation of the disease process and may also contain biochemical, immunological, physiological, morphological, and genetic aspects that add to the progressiveness of the disease. Herein, we summarize findings that highlight the role of dimensions of COPD in the investigation of oxidative stress, inflammatory responses, genetic and epigenetic studies, and pharmacological and dietary antioxidant intervention.
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