Objective: To review some studies about the association between Chlamydia pneumoniae and Coronary artery disease.Methods: To collect,sort and analyze the past study information.Results: Studies suggest that Chlamydia pneumoniae is associated with atherosclerosis,but treatment with a bactericidal antibiotic effective against Chlamydia pneumoniae is not associated with marked reductions of cardiovascular events.Conclusion: It is necessary to revise the significance of preventing cardiovascular events by resisting Chlamydia pneumoniae.