6-wk vs. 12-wk antibiotic therapy increased persistent infection in prosthetic joint infections managed surgically

ACP Journal ClubOctober 20216-wk vs. 12-wk antibiotic therapy increased persistent infection in prosthetic joint infections managed surgicallyVincent J. Mariano, MD, Eleftherios Mylonakis, MD, PhDVincent J. Mariano, MDRhode Island Hospital/ Brown University, Providence, Rhode Island, USA (V.J.M., E.M.)Search for more papers by this author, Eleftherios Mylonakis, MD, PhDRhode Island Hospital/ Brown University, Providence, Rhode Island, USA (V.J.M., E.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJ202110190-116 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationBernard L, Arvieux C, Brunschweiler B, et al. Antibiotic therapy for 6 or 12 weeks for prosthetic joint infection. N Engl J Med. 2021;384:1991-2001. https://pubmed.ncbi.nlm.nih.gov/34042388Clinical Impact RatingsInfectious Disease: References1. Osmon DR, Berbari EF, Berendt AR, et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2013;56:e1-25. [PMID: 23223583] Google Scholar2. Lee RA, Centor RM, Humphrey LL, et al. Appropriate use of short-course antibiotics in common infections: best practice advice from the American College of Physicians. Ann Intern Med. 2021;174:822-7. [PMID: 33819054] Google Scholar3. Li HK, Rombach I, Zambellas R, et al. Oral versus intravenous antibiotics for bone and joint infection. N Engl J Med. 2019;380:425-36. [PMID: 30699315] Google Scholar Author, Article, and Disclosure InformationAffiliations: Rhode Island Hospital/ Brown University, Providence, Rhode Island, USA (V.J.M., E.M.)Disclosures: The commentators have reported no disclosures of interest. The forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-7321.This article was published at Annals.org on 5 October 2021. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics October 2021Volume 174, Issue 10Page: JC116 ePublished: 5 October 2021 Issue Published: October 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...