半胱胺
化学
检出限
荧光
银纳米粒子
纳米颗粒
水溶液
核化学
分析化学(期刊)
色谱法
纳米技术
有机化学
量子力学
物理
材料科学
作者
Xiaowei Mu,Minxing Wu,Bo Zhang,Xin Liu,Shaomei Xu,Yibing Huang,Xinghua Wang,Daqian Song,Pinyi Ma,Ying Sun
出处
期刊:Talanta
[Elsevier]
日期:2021-01-01
卷期号:221: 121463-121463
被引量:39
标识
DOI:10.1016/j.talanta.2020.121463
摘要
In this study, we describe the construction of an “off-on” fluorescent probe based on carbon dots (CDs) and silver nanoparticles (AgNPs) mixture for sensitive and selective detection of cysteamine. By mixing AgNPs with CDs solution, the fluorescence of CDs was significantly decreased due to the inner filter effect (IFE). Upon addition of cysteamine to the mixed aqueous of CDs and AgNPs, the silver-sulfur bond between cysteamine and AgNPs caused AgNPs to aggregate, and the quenched fluorescence of CDs could in turn be recovered. The probe was employed to quantitatively detect cysteamine, and the results showed that it could detect cysteamine in a concentration range of 2–16 μM with the detection limit of 0.35 μM (signal-to-noise ratio of 3). The detection of cysteamine spiked into bovine serum samples showed high recovery rates ranging from 95.5 to 111.7%. More importantly, the developed probe had low cytotoxicity and was successfully used for in vivo imaging of HepG2 cells.
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