The research progression of virus infection and pyroptosis

Pyroptosis is a newly discovered proinflammatory form of programmed cell death. Pyroptosis, which depends on cysteinyl aspartate specific proteinase-1(caspase-1), is inherently the proinflammatory response of the cell.Triggered by various pathological stimuli, pyroptosis is crucial for controlling virus infections.Despite that there are similarities between pyroptosis and necrosis(or apoptosis), there are apparent differences.This review discusses the feature of pyroptosis and the viruses which induce or inhibit pyroptosis. Key words: Pyroptosis; Inflammasome; Caspase-1; IL-1β; IL-18