光学相干层析成像
光学
散光
镜头(地质)
图像质量
材料科学
光学成像
临床前影像学
生物医学工程
3d打印
计算机科学
体内
物理
医学
计算机视觉
图像(数学)
生物
生物技术
作者
Evangelia Gavgiotaki,Radhika K. Poduval,David O. Otuya,Alissa Cirio,Shoumik Lodh,Tyler W. Rihm,Rachel E. Shore,Peter Choy,Sarah L. Silva,Alexander A. Krall,Paola A. Leon Alarcon,Patricia Grahmann,Osman O. Ahsen,Guillermo J. Tearney
摘要
We have previously demonstrated a miniaturized transnasal introduction tube (TNIT) for transnasal endomicroscopy (TNEM) with optical coherence tomography (OCT) for clinical imaging of the small intestine of infants and adults in vivo. Although the TNIT is a convenient and effective way to implement TNEM, OCT probes for imaging through the TNIT had long manufacturing times and low yields, and its multiple cylindrical surfaces caused severe optical aberrations, degrading OCT image quality. Here we introduce a new optical design for 3D-printed microoptics that correct TNIT-induced astigmatism. Preliminary results show that the lens improves resolution and can be reliably manufactured.
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