废水
大型水蚤
化学需氧量
污染物
污水处理
制浆造纸工业
环境化学
流出物
急性毒性
环境科学
毒性
废物管理
化学
环境工程
工程类
有机化学
作者
Jiajia Xue,Dandan Lei,Xiumei Zhao,Yaru Hu,Shijie Yao,Kuangfei Lin,Zejian Wang,Changzheng Cui
出处
期刊:Chemosphere
[Elsevier]
日期:2022-03-01
卷期号:291: 132837-132837
被引量:32
标识
DOI:10.1016/j.chemosphere.2021.132837
摘要
Various pollutants are released during pharmaceutical production processes, which is of great concern. Most studies have focused on the terminal treatment results of mixed pharmaceutical wastewater, and further research on wastewater from the production processes is required. This study investigated the wastewater quality indicators, residual antibiotics, and biological toxicity of the wastewater during the production process in a large pharmaceutical producing factory in Northern China. The wastewater contained numerous organic pollutants, with the chemical oxygen demand (COD) values ranging from 2.0 × 103 to 2.6 × 105 mg L-1 and the total nitrogen (TN) values ranging from 1.3 × 103 to 2.0 × 104 mg L-1. High concentrations of cephalexin and cefradine remained in the wastewater of the production workshop, with the highest concentration of cefradine reaching 1328 mg L-1. The wastewater from the oxidation and solvent recovery workshops was more toxic to Vibrio fischeri and Daphnia magna than that of other workshops. Moreover, the biological acute toxicity of wastewater was significantly correlated with the concentration of COD and TN (p < 0.01). This study provides new insights into the treatment of antibiotic production wastewater, illuminating the incomplete extraction of products and the significant risk posed by pharmaceutical wastewater to the environment.
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