医学
恶病质
肺癌
肌萎缩
癌症
营养不良
免疫疗法
超重
癌症恶病质
重症监护医学
免疫系统
肿瘤科
物理疗法
内科学
肥胖
免疫学
作者
Cinzia Baldessari,Giorgia Guaitoli,Filippo Valoriani,Riccardo Bonacini,Raffaella Marcheselli,Linda Reverberi,Annarita Pecchi,Renata Menozzi,Pietro Torricelli,Federica Bertolini,Fausto Barbieri,Massimo Dominici
标识
DOI:10.1016/j.clnesp.2021.02.017
摘要
Summary
Background and aims
Body composition and balance of nutritional and inflammatory status are important for the immune system. Alterations of these aspects may impact on response, outcome and toxicities of immunotherapy. In this review we try to clarify some definitions and tools used for the assessment of the different aspects of nutritional disorders, body composition and inflammatory status with a focus on lung cancer. Methods
We primary investigate the definitions of malnutrition, cachexia, sarcopenia and overweight. Secondary, tools used to measure body composition, nutritional and inflammatory status, mainly in lung cancer are reviewed. Results
All these features, in the time of precision medicine may improve assessment and selection of patients, incorporating also early palliative care in standard therapy. Conclusions
A multimodal approach based on nutrition assessment and physical exercise should be evaluated to improve aspects of the immune response against cancer and to propose the best treatment to every patient.
科研通智能强力驱动
Strongly Powered by AbleSci AI