A cross-flow rotating packed bed (RPB) was applied to absorb carbon dioxide (CO2) by NaOH solution from gaseous streams. The cross-flow RPB has an inner radius of 2.4 cm, an outer radius of 4.4 cm and an axial height of 12.0 cm. Wire mesh was used as packings. Rotor speeds ranged from 540 to 1600 rpm, providing 11∼ 97 equivalent gravitational force. The removal efficiency of CO2 was determined at various values of operating parameters, including the rotor speed, gas flow rate, liquid flow rate, and NaOH concentration. Our experimental results demonstrated that the removal efficiency of CO2 increased with the rotor speed, liquid flow rate and NaOH concentration; however, decreased with the gas flow rate. Furthermore, a cross-flow RPB provides a reduction in the dosage of the NaOH solution for CO2 absorption, suggesting that a cross-flow RPB has a great potential in the removal of CO2 from the exhausted gases.