干细胞
医学
观点
肌腱
干细胞疗法
组织修复
重症监护医学
生物信息学
神经科学
移植
外科
心理学
生物
生物医学工程
细胞生物学
物理
声学
作者
Lidi Liu,Jennifer Hindieh,Daniel J. Leong,Hui Bin Sun
标识
DOI:10.1016/j.jot.2017.03.007
摘要
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges.
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