A new steroidal saponin from Polygonatum sibiricum

A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2–5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. Their structures were determined by spectroscopical method and by comparison with previously reported spectroscopic data. Compounds 3–5 showed significant cytotoxicity against HepG2 cell lines with IC50 values of 14.2, 12.1 and 8.5 μM, respectively.