Multiple Cross-Coupling Reactions of Aryl and Benzylic Zinc Halides with Aryl Halides and Triflates in Solid-Phase Synthesis of Polyfunctional Aromatics
作者
Mario Rottländer,Paul Knochel
出处
期刊:Synlett [Thieme Medical Publishers (Germany)] 日期:1997-09-01卷期号:1997 (9): 1084-1086被引量:32
标识
DOI:10.1055/s-1997-1529
摘要
All articles of this category Aryl and benzylic zinc bromides undergo efficient Pd(0)-catalyzed cross-coupling reactions on the solid-phase using either Rink or Wang resin. By performing the cross-couplings with the multi-coupling reagents 2 and 3 two successive carbon-carbon bond forming reactions are possible on the solid-phase. solid-phase synthesis - Pd(0)-catalyzed cross-coupling reactions - triflates - multi-coupling reagents