腺泡细胞癌
ETV6
唾液腺
腮腺
融合基因
囊腺癌
乳腺
病理
染色体易位
癌
基因
生物
医学
癌症研究
腺癌
癌症
内科学
遗传学
乳腺癌
粘液表皮样癌
作者
Lilleen Huang,Frederik Petersson,David Loke
标识
DOI:10.1177/0194599812451426a129
摘要
Objective Mammary analogue secretory carcinoma is a new entity in salivary gland tumors that has only been recently described. It has overlapping histopathological features with acinic cell carcinoma and low grade variants of cystadenocarcinoma. It has a distinct chromosomal translocation, t(12;15)‐(p13;q25), resulting in a fusion gene ETV6 NTRK3. The clinical course of this disease entity is uncertain at present. We present a case of MASC of the parotid gland occurring in a 34‐year‐old man and discuss the difficulties in diagnosis and subsequent treatment of this tumour.
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