Humanization of an Anti-CD34 Monoclonal Antibody by Complementarity-determining Region Grafting Based on Computer-assisted Molecular Modelling

Journal Article Humanization of an Anti-CD34 Monoclonal Antibody by Complementarity-determining Region Grafting Based on Computer-assisted Molecular Modelling Get access Sheng Hou, Sheng Hou 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Bohua Li, Bohua Li 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Ling Wang, Ling Wang 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Weizhu Qian, Weizhu Qian 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Dapeng Zhang, Dapeng Zhang 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Xueyu Hong, Xueyu Hong 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Hao Wang, Hao Wang 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yajun Guo Yajun Guo † 1International Joint Cancer Institute, Second Military Medical University, Shanghai 200433, People's Republic of China; and 2Shanghai Center for Cell Engineering and Antibody, Shanghai 201203, People's Republic of China †To whom correspondence should be addressed. Tel: +86-21-25070241, Fax: +86-21-25074349, E-mail: yjguo@smmu.edu.cn Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Biochemistry, Volume 144, Issue 1, July 2008, Pages 115–120, https://doi.org/10.1093/jb/mvn052 Published: 19 April 2008 Article history Received: 25 January 2008 Accepted: 26 March 2008 Published: 19 April 2008