Transient heat transfer from a droplet with heat generation is investigated. It is assumed that the bulk of the thermal resistance resides in the droplet. Two cases were investigated: low Peclet flows and very high Peclet flows. As expected, it was found that the temperature rise due to the heat generation was less for high Peclet flows. In addition, the temperature profile responds more quickly for high Peclet flows. This analysis is also applicable for mass transfer with a zero-order reaction.