化学
催化作用
溴苯
芳基
吡咯
均相催化
产量(工程)
多相催化
碳酰肼
选择性
有机化学
组合化学
铜
同种类的
配体(生物化学)
高分子化学
生物化学
烷基
材料科学
物理
受体
冶金
热力学
作者
Manna Huang,Yi Zhou,Yiqian Wan,Xinhai Zhu
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2018-07-25
卷期号:50 (19): 3911-3920
被引量:8
标识
DOI:10.1055/s-0037-1609578
摘要
A ligand-recyclable, environmentally benign heterogeneous catalyst system composed of CuI and polystyrene-supported N(-(4-(aminomethyl)naphthalen-1-yl)-N(-phenyl-1H-pyrrole-2-carbohydrazide (PSAP) has been established for Ullmann type C–N coupling based on the homogeneous catalyst system N′,N′-diphenyl-1H-pyrrole-2-carbohydrazide/CuI. This heterogeneous catalyst system maintained the catalytic effectiveness of the homogeneous catalyst. A variety of functionalized aryl bromides can be efficiently aminated with aryl amines and aliphatic amines with high selectivity for amines over alcohols. Moreover, a practical application of this catalyst system to promote the reaction of commercially available 4-methoxy-2-methylaniline and bromobenzene in 10 mmol scale, provided 2-methyl-4-methoxydiphenylamine (MMDPA) with 93% yield with the merit of the approach being simple operation for work-up and purification.
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