效应器
纤维化
医学
癌症研究
肝纤维化
成纤维细胞
信号转导
肝纤维化
小学(天文学)
原电池
病理
门静脉
原发性硬化性胆管炎
肝星状细胞
门脉高压
发病机制
作者
Lin Lei,Chenchen Zhao,Wenwen Gao,Guowen Liu,M Y Liu,Guoyue Lv,Zhongqi Fan,Yongkang Cheng,Jinxia Li,Fanrong Kong,Haoping Wang,Xiliang Du,Yuxiang Song,Sara Lemoinne,Axelle Cadoret,Chantal Housset,Xinwei Li
标识
DOI:10.1038/s41467-026-72394-9
摘要
portal fibroblasts as the primary effectors of portal fibrosis and demonstrate that the KLF4/POSTN signaling axis regulates their activation, offering potential therapeutic targets for inhibiting fibrosis in biliary diseases.
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