Objective To evaluate a possible relationship between hyperuricemia (HUA) and meta -bolic syndrome (MS).Methods The prevalence rates of UA and MS were calculated and analyzed in 1278 persons who underwent health check up.Analysis was carried out on the blood uric acid and parameters of MS, and a multiple regression analysis was performed on blood uric acid and HOMA-IR. Results (1) The prevalences of obesity,high WHR, high IFG, HBP,HTG,HTC were significantly higher in high uric acid group that in normal uric acid group.(2)The blood uric acid was positively correlated with HOMA-IR. (3) The prevalence of high uric acid in MS group was significantmy higher than that in the group without MS. Conclusion High uric acid level may be an important factor for development and progress of MS.