Isolation and identification of chemical constituents from bulk of Pinellia ternata

Objective To isolate and identify the chemical constituents of the ethyl acetate extract part of the bulk of Pinellia ternata(Thunb.)Breit.ethanol extract.Methods The compounds were isolated by silica gel column,Sephadex LH-20 column chromatography and HPLC techniques.And these compounds were identified by analysis of their spectral data and chemical properties.Results Ten compounds were obtained and identified as cyclo(Phe-Tyr)(1),cyclo-(Leu-Tyr)(2),2′-deoxyuridine(3),isolariciresinol 9-O-β-D-glucopyranoside(4),isolariciresinol(5),uracil(6),gallic acid(7),uridine(8),adenosine(9)and cyclo-(Val-Tyr)(10).Conclusions Compounds 1,3,4 are all firstly isolated from the Pinellia genus.Compounds 2,7,10 are isolated from this plant for the first time.