细胞毒性T细胞
陆生植物
化学
生物
体外
植物
生物化学
作者
Young‐Won Chin,Kee Dong Yoon,Jinwoong Kim
出处
期刊:Anti-cancer Agents in Medicinal Chemistry
[Bentham Science]
日期:2009-10-01
卷期号:9 (8): 913-942
被引量:24
标识
DOI:10.2174/187152009789124664
摘要
Naturally occurring cytotoxic compounds have been considered to be a valuable pool of lead compounds in the development of potential anticancer drugs. Currently, some cytotoxic compounds of terrestrial plants are being used as cancer therapeutic drugs and more candidates are under clinical trials along with cytotoxic small molecules of terrestrial microorganisms and marine organisms. In the present review, the structures and representative cytotoxicities of new organic small molecules (over 200 molecules) obtained from terrestrial plants between 2001 and 2004 are presented.
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