恩帕吉菲
医学
痛风
尿酸
内科学
肾脏疾病
肾功能
安慰剂
糖尿病
危险系数
内分泌学
高尿酸血症
肌酐
泌尿科
胃肠病学
2型糖尿病
置信区间
病理
替代医学
作者
Kaitlin J. Mayne,Rebecca J. Sardell,Natalie Staplin,Parminder K. Judge,Doreen Zhu,Emily Sammons,David Z.I. Cherney,Jennifer B. Green,Adeera Levin,Roberto Pontremoli,Sibylle J. Hauske,Jonathan Emberson,David Preiss,Martin Landray,Colin Baigent,Christoph Wanner,Richard Haynes,William G. Herrington,the EMPA-KIDNEY Collaborative Group,Colin Baigent
摘要
SGLT2 inhibition reduces serum uric acid in patients with CKD, with larger effects at higher eGFR and in the absence of diabetes. However, the effect on uric acid is modest and did not translate into reduced risk of gout in EMPA-KIDNEY.
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