肠道菌群
心脏毒性
阿霉素
药理学
作文(语言)
癌症研究
化学
毒性
内科学
医学
免疫学
语言学
哲学
化疗
作者
Jianchang Xu,Jiedong Zhou,Jinjin Hao,Zuoquan Zhong,Haowei Wu,Peipei Zhang,Juntao Yang,Hangyuan Guo,Jufang Chi
出处
期刊:American Journal of Physiology-cell Physiology
[American Physiological Society]
日期:2024-01-01
卷期号:326 (1): C161-C176
标识
DOI:10.1152/ajpcell.00477.2023
摘要
This study demonstrated for the first time the protective effect of emodin against DIC and verified by FMT that its cardioprotective effect was achieved by remodeling gut microbiota composition, resulting in attenuation of ferroptosis. Furthermore, we demonstrated that these effects were mediated by the redox-related gene Nrf2.
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