INDETERMINATE CELL HISTIOCYTOSIS WITH OCULAR INVOLVEMENT IN A NEONATE: A CASE REPORT

Purpose: The authors describe a case of Indeterminate cell histiocytosis, a rare disease of histiocytic proliferation on the spectrum of Langerhans cell histiocytosis. Methods: Data were collected through retrospective chart review. Results: The authors present a novel case of congenital Indeterminate cell histiocytosis with multisystem disease, including significant pan-ocular involvement. The neonate was successfully treated with the BRAF-kinase inhibitor dabrafenib, local anti-VEGF, and corticosteroid. Conclusions: The present case expands on the current ocular presentations of Indeterminate cell histiocytosis.