生物结合
化学
点击化学
绿色化学
纳米技术
组合化学
硒
有机化学
催化作用
反应机理
材料科学
作者
Wei Hou,Yiyuan Zhang,Fuchao Huang,Wanting Chen,Yuang Gu,Yan Wang,Jiacheng Pang,Hewei Dong,Kangyin Pan,Shuning Zhang,Peixiang Ma,Hongtao Xu
标识
DOI:10.1002/anie.202404403
摘要
Selenium–nitrogen exchange (SeNEx) chemistry creates seleno-connecting linkage to efficiently explore the organo-Se chemical world. In their Research Article (e202318534), Wei Hou, Hongtao Xu et al. put forward the concept of SeNEx chemistry based on the excellent performance of the reaction between benzoselenazolones and terminal alkynes. This reaction exhibits modularity, robustness, mild reaction conditions, and fast kinetics, and can be used in nanomole-scale parallel synthesis, DNA-encoded library synthesis, and peptide and protein bioconjugation.
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