Next-Generation Metal–Organic Frameworks: Shaping the Future of Steroid Compound Management

纳米技术 生物医学 类固醇 药物输送 表面改性 生化工程 组合化学 临床实习 材料科学 靶向给药 药品 领域(数学) 催化作用 药物开发 化学 类固醇代谢 计算机科学 药物发现
作者
Hong Jiang,Siyan Xu,Xiaomeng Xiang,Mengshi Zhao,Ying Wang,Xiangyu Liu,Bing Liu,Qing Chen
出处
期刊:ACS omega [American Chemical Society]
卷期号:10 (10): 9890-9902 被引量:2
标识
DOI:10.1021/acsomega.4c11671
摘要

Metal-Organic Frameworks (MOFs), as a new type of porous material, have attracted widespread attention in the fields of chemistry, materials science, and biomedicine owing to their unique structural characteristics and potential for functionalization. This review summarizes the latest research progress of MOFs in the field of steroid compounds, including the latest research progress of MOFs in the purification and separation of steroids, sensing and detection, catalytic transformation, and drug delivery. First, we explore how the porous structure and chemical functionalization of MOFs achieve efficient separation and purification of steroid compounds. Second, the high sensitivity and selectivity of MOFs as sensing materials in steroid detection, as well as their application potential in actual sample analysis, are analyzed. Furthermore, the role of MOFs in steroid catalytic transformation reactions is discussed, including their performance as catalysts or catalyst carriers. Finally, we focus on the innovative applications of MOFs in drug delivery systems, especially their advantages in controlled release and targeted drug delivery. This article also explores the future development trends and application prospects of MOFs in the field of steroids, highlighting the challenges and opportunities in material design, functionalization strategies, and practical implementations. Through this review, we aim to provide a comprehensive theoretical basis and practical guidance for further research and application of MOFs in the field of steroids.
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