对映选择合成
异喹啉
磷化氢
化学
催化作用
齿合度
铜
配体(生物化学)
组合化学
有机化学
金属
生物化学
受体
作者
Qingjing Yang,Jian Zhou,Jun Wang
出处
期刊:Chemical Science
[The Royal Society of Chemistry]
日期:2023-01-01
卷期号:14 (16): 4413-4417
被引量:2
摘要
An enantioselective hydrophosphination of alkenyl isoquinolines is developed by using a copper-chiral diphosphine ligand catalyst. It provides a direct and atom-efficient approach to prepare a variety of chiral phosphines with an isoquinoline unit in good yields and high enantioselectivities. In addition, these chiral phosphine products are useful bidentate P,N-ligands which showed potential application in asymmetric catalysis.
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