化学
胺化
原子经济
催化作用
胺气处理
功能群
组合化学
光催化
镍
化学计量学
光催化
协同催化
光化学
有机化学
聚合物
作者
Jie Gao,Xian-Chen He,Yanling Liu,Zhipeng Ye,Jianping Guan,Kai Chen,Hao-Yue Xiang,Hua Ye
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-10-16
卷期号:25 (42): 7716-7720
标识
DOI:10.1021/acs.orglett.3c03073
摘要
Herein, a direct cross-dehydrogenative C–H amination of indoles has been successfully achieved, enabled by the merger of photocatalysis with nickel catalysis. This developed process does not require stoichiometric oxidants and prefunctionalization of amine partners, providing a concise platform for C–N bond formation. Moreover, the synthetic practicality of this transformation was well revealed by its high step- and atom-economy, high reaction efficiency, and broad functional group tolerance.
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