Preparation of Artificial Skin that Mimics Human Skin Surface and Mechanical Properties

人造皮肤 人体皮肤 材料科学 聚氨酯 生物医学工程 润湿 复合材料 经皮失水 角质层 化学 纳米技术 医学 生物 遗传学
作者
Rana Shimizu,Yoshiaki Nonomura
出处
期刊:Journal of Oleo Science [Japan Oil Chemists' Society]
卷期号:67 (1): 47-54 被引量:17
标识
DOI:10.5650/jos.ess17152
摘要

We have developed an artificial skin that mimics the morphological and mechanical properties of human skin. The artificial skin comprises a polyurethane block possessing a microscopically rough surface. We evaluated the tactile sensations when skin-care cream was applied to the artificial skin. Many subjects perceived smooth, moist, and soft feels during the application process. Cluster analysis showed that these characteristic tactile feels are similar to those when skin-care cream is applied to real human skin. Contact angle analysis showed that an oil droplet spread smoothly on the artificial skin surface, which occurred because there were many grooves several hundred micrometers in width on the skin surface. In addition, when the skin-care cream was applied, the change in frictional force during the dynamic friction process increased. These wetting and frictional properties are important factors controlling the similarity of artificial skin to real human skin.

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