To study the sensitivity pattern of Klebsiella pneumoniae to Levofloxacin in a tertiary care hospital. The study was done for a period of 2 years from January 2010 to December 2011. A total number of 945 patients were included in the study. Cases which were culture positive for Klebsiella pneumoniae were identified and their sensitivity pattern for Levofloxacin was assessed. 102 patients were found to be having Klebsiella infection . Among these 102 patients having Klebsiella infection 87 patients (85.3%) were sensitive to Levofloxacin. Klebsiella is sensitive to Levofloxacin. Keywords:- Klebsiella pneumoniae, Levofloxacin, Sensitivity