5-羟色胺能
早泄
射精
神经解剖学
心因性疾病
神经科学
心理学
血清素
医学
内科学
精神科
受体
精神分析
作者
Marcel D. Waldinger,Hemmie H.G. Berendsen,Bertil F.M. Blok,Berend Olivier,Gert Holstege
标识
DOI:10.1016/s0166-4328(97)00183-6
摘要
Premature ejaculation has generally been considered a psychosexual disorder with psychogenic aetiology. Although still mainly treated by behavioural therapy, in recent years double-blind studies have indicated the beneficial effects of some of the serotonergic antidepressants (SSRIs) in delaying ejaculation. We describe here the neurophysiology and the peripheral neuroanatomy of ejaculation and provide a review of the involvement of serotonin in the central nervous system in relation to serotonergic nuclei and their projections. A hypothesis of the role of 5-HT1A and 5-HT2C receptors in premature ejaculation is postulated.
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