Daily Fluctuation in Excretion of Follicle Stimulating and Luteinizing Hormones by a Postmenopausal Woman

The gonadotropin extracts of 24-hr samples of urine of a postmenopausal woman were assayed by a general gonadotropin assay and by assays for follicle stimulating and luteinizing activity. By each of the 3 assay systems it was found that there was a 2-fold fluctuation in the amount of gonadotropin excreted from day to day.