微通道
螺旋(铁路)
机械
横截面(物理)
粒子(生态学)
体积流量
频道(广播)
微流控
流量(数学)
材料科学
水力直径
粒径
涡流
物理
纳米技术
化学
计算机科学
机械工程
电信
地质学
湍流
雷诺数
工程类
海洋学
物理化学
量子力学
作者
Guofeng Guan,Lidan Wu,Ali Asgar S. Bhagat,Zirui Li,Peter C. Y. Chen,Shuzhe Chao,Chong Jin Ong,Jongyoon Han
摘要
The paper reports a new method for three-dimensional observation of the location of focused particle streams along both the depth and width of the channel cross-section in spiral inertial microfluidic systems. The results confirm that particles are focused near the top and bottom walls of the microchannel cross-section, revealing clear insights on the focusing and separation mechanism. Based on this detailed understanding of the force balance, we introduce a novel spiral microchannel with a trapezoidal cross-section that generates stronger Dean vortices at the outer half of the channel. Experiments show that particles focusing in such device are sensitive to particle size and flow rate, and exhibits a sharp transition from the inner half to the outer half equilibrium positions at a size-dependent critical flow rate. As particle equilibration positions are well segregated based on different focusing mechanisms, a higher separation resolution is achieved over conventional spiral microchannels with rectangular cross-section.
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