孟德尔随机化
可药性
肌萎缩
遗传学
基因
孟德尔遗传
生物
计算生物学
生物信息学
遗传变异
基因型
解剖
作者
Jihao Wu,Xiong Chen,Ruijun Li,Qiying Lu,Yucheng Ba,Jiayun M. Fang,Yilin Liu,Ruijie Li,Yixuan Liu,Yiling Wang,Jinsi Chen,Yanbing Li,Yinong Huang
标识
DOI：10.1016/j.metabol.2024.155994
摘要
Our druggable genome-wide MR analysis identifies BORCS7, PM20D1, NUCKS1, and UQCC1 as causally associated with muscle mass and function. These findings offer insights into the genetic basis of sarcopenia, paving the way for these genes to become promising drug targets in mitigating this debilitating condition.
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(2025-6-4)
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