Sulfonyl radicals generation via β-scission

The employment of phosphoranyl reagents generating valuable radical classes via α or β-scission has attracted increasing interest. However, achieving high chemoselectivity remains a significant challenge. The Doyle group demonstrated that aminophosphoranyl radicals produce sulfonamidyl radical via α-scission owing to the weaker P−N bond compared with the N−S bond. Recently, the Hong group has reported the generation of sulfonyl radicals induced by β-fragmentation from aminophosphoranyl radicals under visible light and mild conditions.