Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria

线粒体 癌细胞 血小板 癌症 癌症研究 MFN2型 细胞 医学 化学 生物 免疫学 细胞生物学 内科学 生物化学 线粒体DNA 基因 线粒体融合
作者
Wenkan Zhang,Hao Zhou,Hengyuan Li,Haochen Mou,Eloy Yinwang,Yucheng Xue,Shengdong Wang,Yongxing Zhang,Zenan Wang,Tao Chen,Hangxiang Sun,Fangqian Wang,Jiahao Zhang,Xupeng Chai,Shixin Chen,Binghao Li,Changqing Zhang,Junjie Gao,Zhaoming Ye
出处
期刊:Cell Reports [Cell Press]
卷期号:42 (12): 113464-113464 被引量:4
标识
DOI:10.1016/j.celrep.2023.113464
摘要

(Cell Reports 42, 113147, September 26, 2023) In the originally published version of this article, the picture of H&E in the vehicle group was not shown in Figure 4I, and the inserts of the platelet (normal) group and the platelet (A/R) group were not correct. The corrected figure appears below and also with the paper online. Also, in the originally published version of this article, the email addresses for two of the corresponding authors were incorrect and have now been updated in the paper online. The correct email address for Changqing Zhang is [email protected], and the correct email address for Junjie Gao is [email protected]. The authors apologize for these errors. Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondriaZhang et al.Cell ReportsSeptember 19, 2023In BriefZhang et al. report that cancer cells are reprogrammed to a metastatic state through the acquisition of platelet mitochondria via the PINK1/Parkin-Mfn2 pathway. They discover that transferred platelet mitochondria drive metabolic shift and ROS reduction in cancer cells. Targeting platelet mitochondria is a potential treatment for cancer metastases. Full-Text PDF Open Access
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