杀生物剂
病毒包膜
微生物学
化学
脊髓灰质炎病毒
甲型肝炎病毒
病毒学
病毒
细菌
生物
有机化学
遗传学
作者
Nikolay N Nosik,Д Н Носик,А Я Чижов
出处
期刊:Voprosy virusologii
[Central Research Institute for Epidemiology]
日期:2017-02-20
卷期号:62 (1): 41-45
被引量:5
标识
DOI:10.18821/0507-4088-2017-62-1-41-45
摘要
The main groups of biocide agents used for inactivation of bacteria and viruses were studied for their virucidal activity against enveloped (HIV, viral hepatitis C, influenza virus A) and non-enveloped viruses (poliovirus, adenovirus). Their efficiency was analyzed. Quarterly ammonium compounds (QAC) themselves are not able to properly inactivate non-enveloped viruses. However, they can be successfully applied in combination with other biocides (guanidines, aldehydes). Effective composition of QAC with amines and guanidines provided inactivation of viruses (4.0 lgTCID50) in concentrations of 0.166-0.280% for non-enveloped viruses and 0.080-00.185% for enveloped viruses. The combination of QAC with aldehydes is especially effective (0.04-0.64% for non-enveloped viruses). The virucidal efficiency does not directly depend on the QAC concentration in the chemical disinfectants.
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