生物相容性
材料科学
极限抗拉强度
聚乙烯醇
复合材料
抗压强度
自愈水凝胶
粘附
琼脂糖
模数
杨氏模量
生物医学工程
高分子化学
化学
冶金
医学
色谱法
作者
Jinming Li,Heng Li,Chengwei Wu,Wei Zhang
出处
期刊:Polymer
[Elsevier]
日期:2022-04-01
卷期号:247: 124786-124786
被引量:8
标识
DOI:10.1016/j.polymer.2022.124786
摘要
The self-healing ability of articular cartilage is poor, and hydrogel materials are expected to be used for cartilage replacement due to their high-water content and good biocompatibility. Here, the polyvinyl alcohol-acrylamide-agarose multi-network hydrogel was proposed. The hydrogel has a compressive modulus of 1.19 MPa and a compressive strength limit of 8.87 MPa, as well as a tensile modulus of 0.63 MPa and a tensile strength limit of 1.08 MPa. The mechanical properties of hydrogel meet the requirement for cartilage replacement materials. The in vitro cell experiments indicate that the introduction of agarose improves the cell adhesion of the hydrogel, which is expected to be beneficial in the field of biomedicine.
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