无线
数码产品
压力传感器
柔性电子器件
生物医学工程
材料科学
计算机科学
电气工程
工程类
纳米技术
电信
机械工程
作者
Robert Herbert,Hyo‐Ryoung Lim,Bruno Rigo,Woon‐Hong Yeo
出处
期刊:Science Advances
[American Association for the Advancement of Science (AAAS)]
日期:2022-05-13
卷期号:8 (19)
被引量:44
标识
DOI:10.1126/sciadv.abm1175
摘要
The continuous monitoring of hemodynamics attainable with wireless implantable devices would improve the treatment of vascular diseases. However, demanding requirements of size, wireless operation, and compatibility with endovascular procedures have limited the development of vascular electronics. Here, we report an implantable, wireless vascular electronic system, consisting of a multimaterial inductive stent and printed soft sensors capable of real-time monitoring of arterial pressure, pulse rate, and flow without batteries or circuits. Developments in stent design achieve an enhanced wireless platform while matching conventional stent mechanics. The fully printed pressure sensors demonstrate fast response times, high durability, and sensing at small bending radii. The device is monitored via inductive coupling at communication distances notably larger than prior vascular sensors. The wireless electronic system is validated in artery models, while minimally invasive catheter implantation is demonstrated in an in vivo rabbit study. Overall, the vascular system offers an adaptable framework for comprehensive monitoring of hemodynamics.
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