Clinical analysis on 90 patients with moderate and severe ovarian hyperstimulation syndrome

Objective To investigate the high risk factors,clinical manifestation and treatment of ovarian hyperstimulation syndrome(OHSS) in assisted reproductive techniques.Methods Clinical data of 90 in-hospital OHSS patients from 2000 to 2011 were analysed retrospectively.Results(1) The high risk factors of OHSS:young women,polycystic ovarian syndrome(PCOS),a large number of follicles and pregnancy.(2) Longer disease process,more severe symptoms and larger amount albumin used for treatment of OHSS were observed in pregnant patients compared with non-pregnant ones.The disease process of pregnant patients and non-pregnant patients were(18.56±12.19) and(8.28±3.21)days,respectively.The amount of albumin were(130.43±24.22)g and(257.39±64.35)g.(3)Increasing effective blood volume and human serum albumin through intravenous dripping were the successful treatment of OHSS.Paracentesis was necessary for patients with severe ascites and hydrothorax.Conclusion OHSS is a serious complication of controlled ovarian hyperstimulation,which deserves proper prevention and treatment.