Lumbar precursor B-cell lymphoblastic lymphoma:a case report and review of literature

Objective:To report a case of lumbar precursor B-cell lymphoblastic lymphoma and study its clinical and pathologic features,diagnosis and differential diagnosis.Methods:A case of lumbar precursor B-cell lymphoblastic lymphoma was studied by using light microscopy and immunohistochemical staining,gene rearrangement,with review of literature.Results:The tumor cells with abundant cytoplasm and dust-like chromatin were distributed asystematically and unevenly.Immunophenotype staining showed that the tumor cells were asystematically positive for CD99,LCA,CD20,CD79a and focally positive for CD3.While Vimentin was negative in tumor cells,positive in stroma.Conclusion:Precursor B-cell lymphoblastic lymphoma is a rare malignant tumor.The diagnosis and differential diagnosis are based on pathological morphology and immunophenotype examination.