The experiment adopts Yarrowia lipolytica proved by molecule biotechnology as the research object.Study the treatment effcet of Yarrowia lipolytica at different time,temperature,pH and rotate speed.The result indicate Yarrowia lipolytica has good degradational effect to lipidic organic matter when the inoculative quantity of 4 mL/150 mL and the temperature of 25 ℃ and pH=6 and remaining 50 hours and under 200 r/min,the result is best.