Objective To investigate the relationship between hypertension,insulin resistance and artherosclerosis.Methods Sixty patients with essential hypertension were recruited.According to the level of homeostasis model assessment(HOMA-IR),HOMA-IR≥2.8 as the standard of insulin resistance,twenty-seven patients were classified as essential hypertension with insulin resistance(EH with IR),and thirty-three as essential hypertension without insulin resistance(EH without IR).Another 20 healthy individuals were selected as the control groups.HOMA-IR was calculated as a measture of insulin resistance.Carotid IMT and inner diameter were measured by logic9 colour ultrasonography.Results Common carotid artery IMT(CCA-IMT) in patients of control groups,EH without IR and EH with IR were increased gradually,and compare each of them there is a statistical significance(P0.05).